An Uncommon Oro-cutaneous Complication of Systemic 5-fluorouracil- A Case Report

5-fluorouracil is an antineoplastic drug mainly acts by pyrimidine antagonist and classified as an antimetabolite. There are few complications which is very rare following administration of 5FU including hyper pigmentation, radiation recall, nail discoloration, hand foot syndrome (Palmar plantar erythrodysesthesia). As per our knowledge only one case reported with concurrent of hand foot hyper pigmentation with tongue hyper pigmentation. This is a case report of hyper pigmentation of hand and foot with tongue following administration of systemic 5-fluorouracil.