Novel Wound Dressing Material: Utilising Bio-wastes Enhanced with Spider Web and Magnifera indica (L.) Leaves Extract

Despite significant advancements in wound therapy, the pursuit of innovative wound dressing materials remains fervent. This study aims to analyze the physiochemical characteristics and biological performance of a novel wound dressing material. The material was synthesized using Physiologically Clotted Fibrin (PCF) and Fish Scale Collagen (FSC), bolstered by the medicinal properties of Spider Web (SW) and Ethanolic Extract of Mangifera indica (L.) (EEMI). Infrared spectroscopic analysis confirmed the presence of Type I collagen, while surface morphology revealed a smooth, uniform, and porous structure, demonstrating biocompatibility. Water absorption and porosity measurements met required standards, while antibacterial assays revealed its combat against different bacteria. Additionally, ash tests underscored its eco-friendly nature. Biocompatibility assessments with human erythrocytes showed favourable results. Haemolysis assays at various concentrations and incubation times demonstrated the material's non-haemolytic behaviour. O all, the synthesized biomaterial presents as a promising wound dressing option, boasting efficacy, cost-effectiveness, and environmental sustainability.