Chehal, Aref and Alakkad, Ashraf and Kenja, Madhava Rao and Chintakuntlawar, Ashish (2022) Immunotherapy-Induced Vogt Koyanagi Harada Syndrome: A Case Report. Journal of Advances in Medicine and Medical Research, 34 (22). pp. 316-321. ISSN 2456-8899
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Abstract
This report describes a case of Vogt Koyanagi Harada Disease (VKH) in a 44-year-old male with metastatic gastric carcinoma who presented with sudden onset headache and decreased vision. The patient was treated with first-line standard therapy for stage IV HER2-positive gastric adenocarcinoma and was on maintenance trastuzumab and pembrolizumab for seven months before developing new symptoms. His VKH was diagnosed after multiple imaging and a comprehensive ophthalmologic examination. The patient’s vision and headaches improved with theinitiation of corticosteroid therapy. Although immunotherapy wasdiscontinued,trastuzumab was continuedwith close ophthalmology follow-up. He remains in stable conditiondespitehis cancer. It is critical to consider and recognize immunotherapy-relatedophthalmologic complications immediately, even if they are rare, considering theirimplications. Corticosteroids remain the first-line organ-saving therapy.
Item Type: | Article |
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Subjects: | Bengali Archive > Medical Science |
Depositing User: | Unnamed user with email support@bengaliarchive.com |
Date Deposited: | 14 Mar 2023 11:59 |
Last Modified: | 07 Sep 2024 10:45 |
URI: | http://science.archiveopenbook.com/id/eprint/498 |