Alam, Faruk and Amin, Ruhul and Dey, Biplab Kumar and Yakin, Josef and Das, Smriti Rekha Chanda and Islam, Mohidul and Deka, Himangshu and Borgohain, Republica and Kemisetti, Durgaprasad (2021) Theophylline Derivatives' In-vivo Analgesic and Anti-Inflammatory Activities. Journal of Pharmaceutical Research International, 33 (57A). pp. 144-152. ISSN 2456-9119
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Abstract
The reaction of theophylline and chloro-acetyl chloride produced an exceptional series of substituted theophylline derivatives (3A-3D), followed by ammonium thiocyanate and substituted aromatic aldehyde, and these synthesized derivatives were screened to study their analgesic and anti-inflammatory activities. UV, IR, H-1 NMR, mass spectral data, and CHN activities were used to describe the compounds, which were shown to be considerably efficacious at 100 mg/kg p.o., as well as experimental results that were statistically significant at the p <0.01 and p <0.05 levels.
Item Type: | Article |
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Subjects: | Bengali Archive > Medical Science |
Depositing User: | Unnamed user with email support@bengaliarchive.com |
Date Deposited: | 01 Mar 2023 07:33 |
Last Modified: | 22 May 2024 09:41 |
URI: | http://science.archiveopenbook.com/id/eprint/91 |